Shedding light on glioblastoma cellular heterogeneity
نویسندگان
چکیده
منابع مشابه
Shedding light on glioblastoma cellular heterogeneity.
Cellular heterogeneity is one of the key contributors to poor clinical outcome in glioblastoma (GBM). In this issue Lathia and colleagues report on the development of a novel mouse model where the GFAP-tva mouse harbors a Sox2-EGFP reporter to enable direct visualization of intratumoral cellular heterogeneity in a RCAS-PDGFb-driven GBM model. Cellular heterogeneity is associated with one of the...
متن کاملShedding Light on Light*
There are four books describing early studies and views on light, optics and vision that are considered to be landmarks in this branch of science. The first of these is Euclid’s Optica, published about 300BC, in which he postulated that light travelled in straight lines; he described the laws of reflection and described them mathematically. The second is by Ptolemy. He is best known for his 15 ...
متن کاملShedding light on NSOM.
I took patience and hard work. Now, finally, researchers are seeing some sunshine break through what was once a cloudy beginning for near-field scanning optical microscopy (NSOM). Paul Barbara of the University of Texas–Austin (UT– Austin) is among a group of analytical chemists who have a deep respect for this tool and see it as a technique ripe with potential, ranging from chemistry to physic...
متن کاملShedding Light on Adaptation
One of the most remarkable features of the vertebrate retina is its ability to adapt to ambient illumination. One can read from this page by candlelight or one can read from it on a sunny afternoon, but the page always appears white and the letters black. It is the molecular trickery of light adaptation that enables photoreceptors to evade saturation and accurately report relative contrast even...
متن کاملShedding light on endomitosis.
Zhang et al have taken this transla-tional medicine approach full circle by assessing the capacity of A11 to clear arterial throm-bus in 2 murine stroke models. Although A11 showed considerable promise in these studies, restoring blood flow, for example, when administered 2 hours after carotid artery occlu-sion, the most dramatic and encouraging findings were obtained with a second-generation d...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Neuro-Oncology
سال: 2015
ISSN: 1522-8517,1523-5866
DOI: 10.1093/neuonc/nou361